[TYPO3-core] Could not acquire lock for ClassLoader cache creation

[Brian Lynch]

Error is related to Bug #57463, however the fixed "Locker.php" file did not fix the problem.
The full error text is:

Fatal error: Uncaught exception 'RuntimeException' with message 'Could not acquire lock for ClassLoader cache creation.'
in /htdocs/cmstypo3/typo3/sysext/core/Classes/Core/ClassLoader.php:723 Stack trace: #0
/htdocs/cmstypo3/typo3/sysext/core/Classes/Core/ClassLoader.php(489): TYPO3\CMS\Core\Core\ClassLoader->acquireLock() #1
/htdocs/cmstypo3/typo3/sysext/core/Classes/Core/ClassLoader.php(457): TYPO3\CMS\Core\Core\ClassLoader->buildPackageNamespacesAndClassesPaths() #2
/htdocs/cmstypo3/typo3/sysext/core/Classes/Package/PackageManager.php(147):
TYPO3\CMS\Core\Core\ClassLoader->setPackages(Array) #3 /htdocs/cmstypo3/typo3/sysext/core/Classes/Core/Bootstrap.php(322):
TYPO3\CMS\Core\Package\PackageManager->initialize(Object(TYPO3\CMS\Core\Core\Bootstrap)) #4
/htdocs/cmstypo3/typo3/sysext/core/Classes/Core/Bootstrap.php(233):
TYPO3\CMS\Core\Core\Bootstrap->initializePackageManagement(' in 
/htdocs/cmstypo3/typo3/sysext/core/Classes/Core/ClassLoader.php on line 723

I have two web sites running in separate sub-directories, one works and one does not. I have tired to clear temp files check permissions, etc. and nothing seems to help.

Website does not work, backend does not work, and install does not work. Same Error on all three.

Any Ideas of things I could try and get the site running again?